U01.16.029 Epistaxis (Nosebleed)

Learning Objectives

Master the vascular anatomy of Epistaxis. Distinguish between common anterior bleeds and life-threatening posterior hemorrhages, and identify the specific arterial contributions to the Kiesselbach plexus for the USMLE Step 1.


1. Anterior vs. Posterior Epistaxis

The clinical significance of a nosebleed is largely determined by its anatomical location and the caliber of the vessel involved.

Location Vessel / Source Clinical Features
Anterior (Most Common) Kiesselbach Plexus (at the caudal septum). Usually minor; caused by trauma (nose picking), dry air, or allergic rhinitis.
Posterior (Severe) Sphenopalatine Artery (branch of maxillary artery). Can be life-threatening; often requires packing or surgical ligation. Often associated with hypertension.

2. The Kiesselbach Plexus (Little’s Area)

This area is a highly vascularized region of the anteroinferior nasal septum where several arterial branches anastomose.

Mnemonic: Kiesselbach drives his Lexus with his LEGS

  • L — Superior Labial artery (from Facial a.)
  • E — Ethmoidal arteries (Anterior and Posterior)
  • G — Greater palatine artery
  • S — Sphenopalatine artery

3. Common Etiologies

Nosebleeds are often multifactorial, ranging from simple irritation to benign vascular tumors.

Cause Key Details
Trauma Digital trauma (nose picking) is the #1 cause in children.
Environmental Low humidity/dry air causes mucosal friability.
Juvenile Angiofibroma Benign but highly vascular tumor; classically seen in adolescent males.
Systemic Hypertension, anticoagulation, or Osler-Weber-Rendu syndrome.

Activity:


High-Yield Clinical Pearls:

  • Maxillary Artery: The Sphenopalatine artery is the terminal branch of the maxillary artery. If posterior bleeding cannot be controlled, the maxillary artery may be ligated in the pterygopalatine fossa.
  • Nasal Packing: Anterior packing is common, but posterior packing carries a risk of triggering the nasopulmonary reflex, potentially causing bradycardia or apnea.
  • Septal Perforation: Chronic epistaxis management or cocaine use (vasoconstriction) can lead to septal ischemia and eventual perforation.

Activity: