Viral Infections

 

Common Cutaneous Viral Infections

Cutaneous viral infections are classified by the responsible virus family. Diagnosis is often clinical, but definitive testing includes PCR or Tzanck smear.

Key Viral Dermatoses

Condition Virus Clinical Key
Molluscum Contagiosum Poxvirus Umbilicated, flesh-colored papules.
Herpes Simplex (HSV) HSV-1 / HSV-2 Grouped vesicles on an erythematous base.
Verruca Vulgaris HPV Hyperkeratotic papules with thrombosed capillaries.
Varicella Zoster VZV Dermatomal distribution (Shingles).

Clinical Pearls & Exam Focus

  • Tzanck Smear: Used for HSV/VZV—look for multinucleated giant cells.
  • Molluscum: If generalized/widespread in adults, consider underlying HIV or immunosuppression.
  • HPV: Look for “black dots” (thrombosed capillaries) on scraping—a classic board feature of warts.

High-Yield Exam Pearl:

  • Eczema Herpeticum: A serious HSV infection in patients with underlying atopic dermatitis; presents as monomorphic “punched-out” erosions. Treat immediately with Acyclovir.
  • Herpes Zoster: The “dermatomal” clue is absolute. If it involves the tip of the nose (Hutchinson’s sign), look for ophthalmic zoster involvement.