Substance Abuse and Substance Misuse Disorder

 

Substance Use Disorders (SUD)

Substance Use Disorder (SUD) is a chronic, relapsing brain disease characterized by compulsive substance seeking and use, despite harmful consequences. Diagnosis is based on DSM-5 criteria, reflecting a spectrum from mild to severe.

Key Diagnostic Criteria (DSM-5)

Category Key Indicators
Impaired Control Larger amounts than intended, unsuccessful efforts to cut down, excessive time spent.
Social Impairment Failure to fulfill roles (work/home), giving up important activities, continued use despite problems.
Risky Use Physical/psychological danger, continued use despite physical/psychological exacerbation.
Pharmacological Tolerance and withdrawal symptoms.

Management Principles

  • Assessment: Use validated screening tools like CAGE (for alcohol) or DAST (for drugs).
  • Pharmacotherapy: Targeted treatments are available (e.g., Methadone/Buprenorphine for opioids, Naltrexone/Acamprosate for alcohol).
  • Psychosocial: Cognitive Behavioral Therapy (CBT), Motivational Interviewing (MI), and 12-step facilitation are foundational.
High-Yield Clinical Notes:

  • Harm Reduction: Focuses on minimizing the negative health and social impacts of substance use (e.g., needle exchange, supervised consumption) for those not ready for abstinence.
  • Dual Diagnosis: Many patients with SUD have co-occurring psychiatric conditions (e.g., depression, PTSD). Effective treatment must address both concurrently.
  • Relapse: Must be viewed as a clinical event rather than a moral failure; it typically requires adjustment to the treatment plan.