Phrynoderma

 

Phrynoderma (Toad Skin)

A form of follicular hyperkeratosis historically linked to Vitamin A deficiency, though contemporary research suggests it may involve a complex interplay of multiple nutritional deficiencies (e.g., essential fatty acids, B-complex vitamins).

Key Clinical Features

  • Appearance: Multiple, firm, discrete, hyperkeratotic papules that are follicularly centered.
  • Texture: Gives the skin a rough, “toad-like” feel, particularly when stroked.
  • Distribution: Most commonly found on the extensor surfaces of the extremities (elbows, knees) and the buttocks.

Diagnostic & Management Pearls

Aspect Details
Diagnosis Primarily clinical, based on physical exam in the context of malnutrition.
Treatment Correction of underlying nutritional deficiencies (balanced diet, vitamin supplementation).
High-Yield Exam Pearl:

  • Differential Diagnosis: Must be distinguished from Keratosis Pilaris, which is a common, often genetic condition rather than a sign of systemic malnutrition.
  • Vitamin A: Classically associated with Vitamin A deficiency, which also presents with xerophthalmia (dry eyes) and night blindness.