Oxygen Therapy

Oxygen therapy aims to maintain adequate tissue oxygenation and correct hypoxemia. The delivery method is selected based on the required Fraction of Inspired Oxygen (FiO_2) and the patient’s respiratory status.


Device Approx. FiO_2 Clinical Use
Nasal Cannula 24% – 44% Low-flow, comfortable, suitable for stable patients.
Simple Face Mask 40% – 60% Moderate oxygen requirement.
Venturi Mask 24% – 60% Precise, fixed FiO_2 delivery; ideal for COPD.
Non-Rebreather Mask 60% – 90%+ High-flow; emergency use for severe hypoxemia.


High-Yield Clinical Notes:

  • Hypoxic Drive: In chronic hypercapnic respiratory failure (e.g., severe COPD), excessive oxygen can reduce the respiratory drive; monitor PaCO_2 and target a lower SpO_2 (88%–92%).
  • Safety: Oxygen supports combustion. Ensure no open flames or sparking equipment near the oxygen source.
  • Humidification: Highly recommended for flow rates > 4\ L/min to prevent drying of the nasal mucosa and thickening of secretions.

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