Dynamics of transmission

 

NEET PG High-Yield: Dynamics of Transmission

Understanding how infectious agents spread is essential for disease control. This revolves around the Chain of Infection.

The Chain of Infection

Link Definition / Example
Reservoir Habitat (Human, Animal, Environment).
Exit Portal Respiratory, GI, skin, or transplacental.
Transmission Direct (contact, droplet) vs. Indirect (vehicle, vector, airborne).
Entry Portal Usually, the same as the exit portal (e.g., mouth, nose).
Susceptible Host Individuals lacking immunity (age, nutrition, genetics).
High-Yield NEET PG Pearls:

  • Incubation Period: Time from infection to appearance of first symptoms.
  • Serial Interval: Time between successive cases in a chain of transmission.
  • Herd Immunity: The resistance of a group to invasion/spread of an infectious agent, based on a high proportion of immune individuals.
  • Basic Reproduction Number ($R_0$): The average number of secondary cases produced by a single primary case in a completely susceptible population.