Alopecia

 

Alopecia (Hair Loss)

Hair loss is categorized clinically as either non-scarring (follicles preserved) or scarring (follicular destruction). Accurate classification is key to guiding management.

Primary Classifications

Condition Type Clinical Features
Alopecia Areata Non-scarring Well-demarcated patches; “Exclamation point” hairs.
Androgenetic Non-scarring Miniaturization; male/female pattern thinning.
Telogen Effluvium Non-scarring Diffuse shedding after stress/illness/pregnancy.
Discoid Lupus Scarring Erythema, atrophy, and follicular plugging.

Diagnostic Pearls

  • Pull Test: Gently pulling ~50 hairs; >6 hairs coming out suggests active shedding (common in Telogen Effluvium or Alopecia Areata).
  • Scarring vs. Non-Scarring: A clinical sign of scarring is the absence of follicular ostia (the tiny pores where hair exits) on exam. A biopsy is indicated for suspected scarring alopecia to prevent permanent loss.
High-Yield Exam Pearl:

  • Alopecia Areata: Frequently associated with other autoimmune diseases, such as **Vitiligo** and **Thyroiditis**.
  • Trichotillomania: Characterized by hairs of varying lengths (due to pulling) in an irregular, patchy distribution; biopsy would show normal follicles (no inflammation).