U01.03.018 Bacterial endotoxin
Bacterial endotoxins are lipopolysaccharide (LPS) molecules found in the outer membrane of Gram-negative bacteria. The lipid A component is toxic and responsible for activating macrophages and the complement system, leading to fever, hypotension, disseminated intravascular coagulation (DIC), and septic shock.
Question tags bacterial endotoxin, Bacterial Toxins, complement activation, DIC, gram negative bacteria, IL1, IL6, immune response, immunology, lipid A, lipopolysaccharide, macrophage activation, Medical Education, medical microbiology, microbiology, pathophysiology, sepsis, septic shock, Step 1, TNF alpha, USMLE
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