Learning Objective:
Understand and calculate Filtration Fraction (FF) — the proportion of plasma that is filtered through the glomerulus.
Formula:
Explanation:
= Filtration Fraction
= Glomerular Filtration Rate
= Renal Plasma Flow
It represents the fraction of renal plasma flow that becomes glomerular filtrate.
Concept Summary:
- Normal FF ≈ 20% (i.e., ~20% of plasma entering glomeruli is filtered).
- Changes in afferent/efferent arteriolar tone can alter FF:
- ↑ Efferent constriction → ↑ GFR → ↑ FF
- ↑ Afferent constriction → ↓ GFR → ↓ FF
Example:
Given:
✅ Answer: Filtration Fraction = 20%








