U01.21.013 Number Needed to Harm (NNH)

Understand and apply the formula for calculating Number Needed to Harm (NNH), which indicates how many patients need to be exposed to a risk factor or treatment for one additional person to be harmed.


Formula:

NNH = frac{1}{AR}


Explanation:

  • AR = Attributable Risk (difference in risk of adverse outcomes between exposed and unexposed groups)
  • NNH quantifies the harm potential of an exposure or treatment.
  • Higher NNH → safer exposure (fewer people harmed)
  • Lower NNH → more harmful exposure

Example:

Given:
AR = 0.05 (5% additional risk in the exposed group)

NNH = frac{1}{0.05} = 20

Answer: NNH = 20
→ For every 20 people exposed, 1 additional person is harmed due to the exposure.


Activity:


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