U01.21.002 Half-life (t½)

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Learning Objective:
Understand and apply the formula for drug elimination half-life in relation to volume of distribution (Vd) and clearance (CL).

Formula:

t_{1/2} = 0.7 times frac{V_d}{CL}

Example:

Given:
V_d = 50 text{ L}
CL = 5 text{ L/h}

t_{1/2} = 0.7 times frac{50}{5} = 0.7 times 10 = 7 text{ h}

✅ Answer: Half-life = 7 hours

Activity:

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