Learning Objective
Understand the microbiological characteristics, typical habitat, and clinical significance of Staphylococcus saprophyticus as a cause of uncomplicated urinary tract infections in young women.
Staphylococcus saprophyticus
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Characteristics: Gram-positive cocci in clusters; catalase-positive, coagulase-negative, urease-positive; novobiocin-resistant.
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Habitat: Normal microbiota of the female genital tract and perineum.
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Clinical Significance: The Second most common cause of uncomplicated urinary tract infections in young females (after Escherichia coli).
Activity
High-Yield Point for Step 1
Novobiocin resistance distinguishes S. saprophyticus from S. epidermidis.
