M04.04.033 Other Factors Changing the ECG

Learning Objective

After completing this section, learners will be able to identify how ST-segment changes and electrolyte disturbances (potassium and calcium) affect the ECG and recognize their characteristic patterns.


ST Segment Changes

ST Elevation:

  • Causes: Transmural myocardial infarction, Prinzmetal angina (coronary vasospasm)

ST Depression:

  • Causes: Subendocardial ischemia, exertional (stable) angina

Potassium (K⁺)

Hyperkalemia:

  • Accelerates repolarization → tall, peaked T waves, shortened QT interval

Hypokalemia:

  • Slows repolarization → prominent U waves, prolonged QT interval

Calcium (Ca²⁺)

Hypercalcemia:

  • Decreases the QT interval

Hypocalcemia:

  • Increases the QT interval

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