M01.05.022 Tracheobronchial Tree

Learning Objective:

Understand the structure, anatomical position, neurovascular supply, and clinical relevance of the trachea, bronchi, and bronchioles.


The Tracheobronchial Tree

The trachea, bronchi, and bronchioles form the tracheobronchial tree – a system of airways that allow passage of air into the lungs, where gas exchange occurs. These airways are located in the neck and thorax.

This article outlines their anatomical position, structure, neurovascular supply, and clinical relevance.


The Trachea

Anatomical Position

The trachea arises at the lower border of the cricoid cartilage. It descends into the superior mediastinum, bifurcating at the level of the sternal angle to form the right and left main bronchi. It lies anterior to the oesophagus and inclines slightly to the right.

Structure

The trachea is supported by C-shaped cartilage rings, with free ends bridged by the trachealis muscle. It is lined by ciliated pseudostratified columnar epithelium with goblet cells forming the mucociliary escalator, which traps and removes particles.

The carina, at the bifurcation of the trachea, is the most sensitive area for triggering the cough reflex.

Neurovascular Supply

Sensory innervation: recurrent laryngeal nerve
Arterial supply: tracheal branches of the inferior thyroid artery
Venous drainage: brachiocephalic, azygos, and accessory hemiazygos veins


Activity


Bronchi

Structure

At the sternal angle, the trachea bifurcates into the right and left main bronchi, which branch into secondary (lobar) bronchi and tertiary (segmental) bronchi. A segmental bronchus supplies each bronchopulmonary segment – the functional unit of the lungs.

The right main bronchus is wider, shorter, and more vertical than the left, predisposing to foreign body inhalation.

Neurovascular Supply

Innervation: pulmonary branches of the vagus nerve (CN X)
Arterial supply: bronchial arteries
Venous drainage: bronchial veins


Activity


Bronchioles

Structure

The smallest airways, bronchioles, lack cartilage and goblet cells. Club cells produce surfactant to prevent airway collapse.

Conducting bronchioles transport air; terminal bronchioles branch into respiratory bronchioles with alveoli – the site of gas exchange. Adults have ~300 million alveoli.


Clinical Correlations: Asthma

Asthma is a chronic inflammatory disorder causing airway hypersensitivity, reversible obstruction, and bronchospasm.

  • Small airway remodelling includes thickened smooth muscle, damaged epithelium, and thickened basement membrane.
  • Acute “asthma attacks” are triggered by allergens, exercise, or irritants, causing bronchospasm and difficulty breathing with wheezing.

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