M01.02.034 The Eyeball

Learning Objective: To understand the anatomical layers, internal structures, and vascular supply of the eyeball, and recognise key clinical conditions such as glaucoma and papilledema.


The eyeball is a bilateral spherical organ responsible for vision, housed within the bony orbit. Anatomically, it consists of three layers: the fibrous, vascular, and inner layers.


Layers of the Eyeball

Fibrous Layer

The outermost layer, composed of the sclera and cornea.

  • Sclera: The white, opaque portion (≈85% of the fibrous layer). Provides shape and attachment to the extraocular muscles.
  • Cornea: Transparent, central structure responsible for refracting incoming light.

Vascular Layer

Located beneath the fibrous layer, composed of the choroid, ciliary body, and iris.

  • Choroid: A highly vascular layer supplying the outer retina.
  • Ciliary body: Contains smooth muscle (controls lens shape) and ciliary processes (produce aqueous humor).
  • Iris: Pigmented diaphragm surrounding the pupil; controls pupil diameter via autonomic innervation.

Inner Layer (Retina)

The retina has:

  • Pigmented layer: Absorbs light, prevents scattering.
  • Neural layer: Contains photoreceptors. Present only posteriorly and laterally.

Key structures:

  • Macula: Central region for high acuity vision.
  • Fovea: Depression within macula; dense cone concentration.
  • Optic disc: Entry point of optic nerve; lacks photoreceptors (“blind spot”).

ACTIVITY


Structures of the Eyeball

Vitreous Body

Gel-like structure fills the posterior segment. Contains the hyaloid canal (fetal remnant). Functions:

  • Supports lens
  • Stabilizes retina
  • Contributes to optical properties

Lens

Transparent biconvex structure located between the vitreous body and the pupil.

  • The shape alters due to ciliary muscle activity (accommodation).
  • Aging causes opacification → cataracts.

Anterior & Posterior Chambers

Filled with aqueous humor, produced by the ciliary processes.

  • Anterior chamber: Between the cornea and iris
  • Posterior chamber: Between the iris and the ciliary body

Aqueous humor drains via the trabecular meshwork. Obstruction → glaucoma.


Vasculature

  • Ophthalmic artery supplies the eye; key branch = central retinal artery (occlusion → sudden blindness).
  • Superior and inferior ophthalmic veins drain into the cavernous sinus.

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Clinical Relevance

Glaucoma

Characterized by optic nerve damage from increased intraocular pressure.

  • Open-angle: Gradual peripheral vision loss.
  • Closed-angle: Rapid, painful rise in pressure → emergency.

Papilloedema

Swelling of the optic disc due to raised intracranial pressure.

Causes:

  • Mass lesions
  • Haemorrhage
  • Meningitis
  • Hydrocephalus

Venous congestion → retina swelling → blurred margins of optic disc.


ACTIVITY


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